ABSTRACT
Guillain-Barré syndrome and its variants are among the neurological complications induced by SARS-CoV-2. A 49-year-old woman with COVID-19. After 14 days of presenting respiratory symptoms, she started with paresthesias, facial and limb weakness, dysphagia, ataxia, and respiratory failure. An unusual picture of overlapping Guillain-Barré and Miller Fisher syndromes was diagnosed. Nerve conduction study showed myelin damage. IgEV was used, recovery started one week after starting treatment. Guillain-Barré syndrome and its variants are a complication of COVID-19 whose diagnosis can become more complex in cases of unusual presentation where different clinical subtypes overlap. © 2022 Asociación Colombiana de Medicina Crítica y Cuidado lntensivo